"Screening Methods in Pharmacology" provides an up to-date and concise account of in vivo methods used in the pharmacological screening of important categories of clinically useful drugs. It also encompasses the basic principles of animal experimentation and current advances leading to the use of transgenic animals, combinatorial chemistry, high throughout screening, pharmacogenomics, proteomics and array technology. The methods used for the detection of pharmacological effects of potential drugs on the CNS, CVS, endocrines, respiratory tract and immunomodulation have been described in adequate details with cross references for further studies and comprehension. The book is expected to be extremely useful for postgraduates in pharmacology from all disciplines and for the scientists engaged in the drug discovery research programmes.
N. S. ParmarA .: Director, Institute of Pharmaceutical Sciences University of Science & Technology Shiv Prakash.: Managing Director, Synchron Research Services Pvt. Ltd. Sarkhej-Gandhinagar Highway, Bodakdev
Foreword / Preface / Drug Discovery Process: An Introduction / Current Status of Approaches in Drug Discovery / Laboratory Animals / Transgenic Animals / Evaluation of Drugs Acting on Central Nervous System / Evaluation of Drugs Acting on Peripheral Nervous System / Evaluation of Drugs Acting on the Cardio Vascular System / Evaluation of Drugs Acting on Respiratory System / Evaluation of Analgesics, Anti-inflammatory and Antipyretic Activity / Evaluation of Drugs Acting on Urinary Tract / Evaluation of Drugs Acting on Gastro-intestinal System / Evaluation of Drugs Acting on Liver / Anti-diabetic Activity / Antiatherosclerosis/ Anti-hyperlipedemic Activity / Antifertility Activity / Evaluation of Drugs Acting on Eye / Antistressor and Antioxidant Activity / Statistical Analysis / Experimental Design / Annexure / Index.