As part ofthe Annals of the New York Academy of Sciences series, this volumeexamines mechanisms involved in bone development and restructuring,including cellular and mechanical triggers, receptors, andsignalling pathways. This volume also examines otherfactors associated with bone and musculoskeletal health, includingphysiological systems and disease states such as the immune system,inflammation, diabetes, infection and cancer. This book is ideal for Graduatestudents, medical students, researchers and clinicians in with aninterest in anatomy, physiology, developmental biology, immunology,and musculoskeletal health NOTE:Annals volumes are available for sale as individual books or as ajournal. For information on institutional journal subscriptions,please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact theNew York Academy of Sciences directly to place your order (www.nyas.org ). Members of the New York Academy ofScience receive full-text access to the Annals online and discountson print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information aboutbecoming a member.