Targeted Molecular Imaging: Principles and Applications presents the basic science behind personalized cancer medicine and accelerating drug approval from bench to clinic through the application of molecular imaging science and technology. Topics to be covered include the application of gamma scintigraphy (PET and SPECT) in oncology, the effect of contrast agents in PET/CT, radiation dosimetric determination for radiotheranostic agents, imaging technology in drug development, validation of imaging agents on new molecular targets, and economic potential for the development of molecular targeting agents and the process and requirements for FDA compliance.
Imaging Molecular Targets and Clinical Applications in Oncology.- Molecular Targets for Cancer Imaging and Therapy Applications.- Imaging Technologies in Personalized Cancer Medicine Development.- Issues of Radiopharmaceutical Development from Bench to Clinic.- Imaging of Apoptosis and Hypoxia.- Imaging of Angiogenesis.- Imaging of Cell Proliferation in Oncology.- Imaging of Signal Transduction in Oncology.- Imaging of Stem Cells in Oncology.- Imaging of Anticancer Drugs, Response, and Prognosis.- Imaging of Soft Tissue Sarcoma.- Imaging of Amyloid Plaque.- Imaging Bone Metastasis.- Transporters-based Kit Radiotracers for Molecular Imaging in Oncology.- Radiotheranostics in Oncology.- Radiopharmaceutical Automation and Regulatory Compliance.- Molecular Imaging with High Resolution Semiconductor Animal PET.- PET/CT Imaging Artifacts.- Radiation Dosimetric Determination from Animal to Human.- Clinical Molecular Imaging and Validation of Molecular Targets.- Economic Opportunities in Molecular Imaging
Softcover reprint of the original 2nd ed. 2012