Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. Both Volume 1 and Volume 2 of this proceedings are included in this set. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L'Amoreaux, College of Staten Island, were co-chairs of the Organizing Committee for the meeting.
Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.
26. Neuropsychopharmacological Actions Of Taurine.- Taurine And Its Neuroprotective Role.- Antidepressant-Like Effect Of Chronic Taurine Administration And Its Hippocampal Signal Transduction In Rats.- Direct Interaction Of Taurine With The Nmda Glutamate Receptor Sub-Type Via Multiple Mechanisms.- The Modulatory Role Of Taurine In Retinal Ganglion Cells.- Taurine Is A Crucial Factor To Preserve Retinal Ganglion Cell Survival.- Taurine Regulation Of Voltage-Gated Channels In Retinal Neurons.- The Effect Of Folic Acid On Gabaa-? 1 Receptor Subunit.- Taurine Counteracts The Suppressive Effect Of Lipopolysaccharide On Neurogenesis In The Hippocampus Of Rats.- Perinatal Taurine Exposure Programs Patterns Of Autonomic Nerve Activity Responses To Tooth Pulp Stimulation In Adult Male Rats.- Regulation Of Taurine Release In The Hippocampus Of Developing And Adult Mice.- Evaluation Of The Taurine Concentrations In Dog Plasma And Aqueous Humor: A Pilot Study.- Protective Effect Of Taurine On Down-Regulated Expression Of Thyroid Hormone Receptor Genes In Brains Of Mice Exposed To Arsenic.- Taurine Exerts Robust Protection Against Hypoxia And Oxygen/Glucose Deprivation In Human Neuroblastoma Cell Culture.- The Effects Of Chronic Taurine Supplementation On Motor Learning.- Changes In Gene Expression At Inhibitory Synapses In Response To Taurine Treatment.- Taurine Effects On Emotional Learning And Memory In Aged Mice: Neurochemical Alterations And Differentiation In Auditory Cued Fear And Context Conditioning.- Rising Taurine And Ethanol Concentrations In Nucleus Accumbens Interact To Produce The Dopamine Activating Effects Of Alcohol.- Thiotaurine Prevents Apoptosis Of Human Neutrophils: A Putative Role In Inflammation.- Protection By Taurine Against Inos-Dependent Dna Damage In Heavily Exercised Skeletal Muscle By Inhibition Of The Nf-? ?B Signaling Pathway.- Effect Of Taurine Chloramine On Differentiation Of Human Preadipocytes Into Adipocytes.- Taurine Chloramine Administered In Vivo Increases Nrf2-Regulated Antioxidant Enzyme Expression In Murine Peritoneal Macrophages.- Influence Of Taurine Haloamines (Taucl And Taubr) On The Development Of Pseudomonas Aeruginosa Biofilm - A Preliminary Study.- Inhibitory Effects Of Taurine On Stz-Induced Apoptosis Of Pancreatic Islet Cells.- Taurine's Effects On The Neuroendocrine Functions Of Pancreatic ? Cells.- Anti-Diabetic Effect Of Taurine In Cultured Rat Skeletal L6 Myotubes.- Protection By Taurine And Thiotaurine Against Biochemical And Cellular Alterations Induced By Diabetes In A Rat Model.- The Effects Of Taurine And Thiotaurine On Oxidative Stress In The Aorta And Heart Of Diabetic Rats.- Comparative Evaluation Of Taurine And Thiotaurine As Protectants Against Diabetes-Induced Nephropathy In A Rat Model.- Taurine May Not Alleviate Hyperglycemia-Mediated Endoplasmic Reticulum (Er) Stress In Human Adipocytes.- 27. Taurine, Glutathione And Bioenergetics.- Molybdenum Cofactor Deficiency: Metabolic Link Between Taurine And S-Sulfocysteine.- Taurine And Chinese Traditional Medicine Accelerate Alcohol Metabolism In Mice.- Taurine And Chinese Traditional Medicine Accelerate Alcohol Metabolism In Mice.- The Effect Of Long-Term Taurine Supplementation And Fructose Feeding On Glucose And Lipid Homeostasis In Wistar Rats.- Effect Of Taurine Feeding On Bone Mineral Density And Bone Markers In Rats.- The Effects Of Bisphosphonates On Taurine Transport In Retinal Capillary Endothelial Cells Under High Glucose Conditions.- Perinatal Taurine Imbalance Alters The Interplay Of Renin-Angiotensin System And Estrogen On Glucose-Insulin Regulation In Adult Female Rats.- Reduced Placental Taurine Transporter (Taut) Activity In Pregnancies Complicated By Pre-Eclampsia And Maternal Obesity.- Effects Of Taurine Supplementation Upon Food Intake And Central Insulin Signaling In Malnourished Mice Fed On A High Fat Diet.- Positive Correlation Between Serum Taurine And Adiponectin Levels In High-Fat-Induced Obesity Rats.- Relationship Among Serum Taurine, Serum Adipokines And Body Composition During 8-Week Human Body Weight Control Program.- Dietary Taurine And Nutrients Intake And Dietary Quality By Alcohol Consumption Level In Korean Male College Students.- Taurine Supplementation Restores Insulin Secretion And Reduces Er Stress Markers In Protein-Malnourished Mice.- Taurine As A Marker For The Identification Of Natural Calculus Bovis And Its Substitutes.- Taurine Deficiency And Melas Are Closely Related Syndromes.- Antioxidant And Dna Protection Effects Of Taurine By Electron Spin Resonance Spectroscopy.- Additional Effects Of Taurine On The Benefits Of Bcaa Intake For The Delayed-Onset-Muscle Soreness And Muscle Damage Induced By High-Intensity Eccentric Exercise.- Taurine Enhances Anticaner Activity Of Cisplatin In Human Cervical Cancer Cells.- Comparative Evaluation Of The Effects Of Taurine And Thiotaurine On Alterations Of The Cellular Redox Status And Activities Of Antioxidant And Glutathione-Related Enzymes By Acetaminophen In The Rat.- Effects Of Taurine On Myocardial Cgmp/Camp Ratio, Antioxidant Ability And Ultrastructure In Cardiac Hypertrophy Rats Induced By Isoproterenol.- Protective Effect Of Taurine On Tri-Ortho-Cresyl Phosphate (Tocp) Induced Cytotoxicity In C6 Glioma Cells.- The Mechanism Of Taurine Protection Against Endoplasmic Reticulum Stress In An Animal Stroke Model Of Cerebral Artery Occlusion And Stroke-Related Conditions In Primary Neuronal Cell Culture.- Relationship Among Self-Reported Fatigue, Dietary Taurine Intake And Dietary Habits In Korean College Students.- Simulative Evaluation Of Taurine Against Alopecia Caused By Stress In Caenorhabditis Elegans.- Protective Effect Of Taurine On The Decreased Biogenic Amine Neurotransmitter Levels In Brain Of Mice Exposed To Arsenic.- Differential Regulation Of Taut By Calcitriol And Retinoic Acid Via Vdr/Rxr In Llc-Pk1 And Mcf-7 Cells.- Knockdown Of Taut Expression Impairs Human Embryonic Kidney 293 Cell Development.- The Role Of Taurine On Skeletal Muscle Cell Differentiation.- Taurine And Fish Development: Insights For The Aquaculture Industry.- Effect Of Dietary Taurine And Arginine Supplementation On Bone Mineral Density In Growing Female Rats.- Taurine Enhances The Sexual Response And Mating Ability In Aged Male Rats.