The use of chemicals in the workplace is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the safe handling and use of chemicals. In practice, a range of information is required when assessing the safe handling of chemicals, much of which is provided by the manufacturer in the material safety data sheet. "Toxicology and Ecotoxicology in Chemical Safety Assessment" is written for corporate health and safety officers and safety managers, R&D chemists, process chemists and engineers, and manufacturing unit managers and supervisors in all industries where chemicals are used.The information contained in this book will help those personnel understand, interpret and apply the range of information supplied on a material safety data sheet when planning the safe handling and use of chemicals. It provides detailed practical guidance in using supplier Tox/Ecotox data when assessing the risks associated with the industrial handling and use of chemicals. Data from different manufacturers is often compiled to different standards, using different methodologies.
This book will provide the reader with a detailed framework within which to evaluate the data supplied. It helps readers to plot a commercially realistic path between over- and under-evaluation of the risks and hazards associated with the industrial handling and use of chemicals.
Laura Robinson is an independent consultantand Ian Thorn is at Eka Chemicals, Weston-Super-Mere, UK
1. Toxicology.Introduction.Toxicity.Chemical irritancy and corrosive effects.Chemical allergies.Genetic toxicology and carcinogenicity.Reproductive toxicology.The nervous system.Alternatives to animal testing.2. Ecotoxicology.Introduction.Aquatic toxicity testing.Chemical persistence and biodegradability.Bioaccumulation.3. Classification and labelling of chemicals according to their hazardous nature.Introduction.Europe.The Dangerous Substances Directive 67/548/EEC.Preparations.Canada.USA.Summary.4. Handling chemicals in the workplace.Introduction.Risk assessment.Chemical harzards..5. Chemical control.Introduction.Chemical control in Europe.Chemical control in the USA.Chemical control in Australia.6. The Material Safety Data Sheet.Introduction.How to deal with differences in toxicological information