The second edition of Virology is an accessible introduction designed to enable students to understand the principles of virus structure, replication and genetics. The aim of this book is to help the reader appreciate the relevance of virology in the modern world, including the fields of vaccines, anti-viral drugs and cancer. There is also a chapter on prions. The second edition has been extensively revised and updated to reflect the many developments in virology and offers deeper insights into the subject. Newly-discovered viruses are discussed and there is an additional chapter on the influenza virus.
Dr Caroline Griffiths, Senior Lecturer in Virology and Molecular Biology, Oxford Brookes University
Preface to Second Edition xix Preface to First Edition xxi Abbreviations Used in This Book xxiii Greek Letters Used in This Book xxvii Color Coding for Molecules xxix Chapter 1 Viruses and Their Importance 1 Chapter 2 Methods Used in Virology 9 Chapter 3 Virus Structure 27 Chapter 4 Virus Transmission 45 Chapter 5 Attachment and Entry of Viruses into Cells 55 Chapter 6 Transcription, Translation, and Transport 65 Chapter 7 Virus Genome Replication 83 Chapter 8 Assembly and Exit of Virions from Cells 93 Chapter 9 Outcomes of Infection for the Host 101 Chapter 10 Classification and Nomenclature of Viruses 115 Chapter 11 Herpesviruses (and Other dsDNA Viruses) 121 Chapter 12 Parvoviruses (and Other ssDNA Viruses) 135 Chapter 13 Reoviruses (and Other dsRNA Viruses) 145 Chapter 14 Picornaviruses (and Other Plus-Strand RNA Viruses) 155 Chapter 15 Rhabdoviruses (and Other Minus-Strand RNA Viruses) 169 Chapter 16 Influenza Virus 183 Chapter 17 Retroviruses 195 Chapter 18 Human Immunodeficiency Viruses 207 Chapter 19 Hepadnaviruses (and Other Reverse-Transcribing DNA Viruses) 223 Chapter 20 Bacterial Viruses 237 Chapter 21 Origins and Evolution of Viruses 263 Chapter 22 Emerging Viruses 277 Chapter 23 Viruses and Cancer 289 Chapter 24 Survival of Infectivity 301 Chapter 25 Virus Vaccines 307 Chapter 26 Anti-viral Drugs 315 Chapter 27 Prions 327 Virologists Vocabulary 335 Index 347