Williams Hematology, 9E (9th edition)

Williams Hematology, 9E (9th edition)

By: Josef Prchal (author), Marshall Al Lichtman (author), Kenneth Kaushansky (author), Marcel M. Levi (author), Michael A. Caligiuri (author), Linda J. Burns (author), Oliver W. Press (author)Hardback

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Description

The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2017! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.

About Author

Kenneth Kaushansky, MD (Stony Brook, NY) is Senior Vice President, Health Sciences and Dean of the School of Medicine, Stony Brook University. Marshall A. Lichtman, MD (Rochester, NY) is Professor of Medicine and of Biochemistry and Biophysics, University of Rochester Medical Center. Josef T. Prchal, MD (Salt Lake City, UT, and Prague, Czech Republic) is Professor of Medicine, Pathology, and Genetics, Hematology Division of the University of Utah, and Department of Pathophysiology, First Faculty of Medicine, Charles University in Prague. Marcel M. Levi, MD, PhD (Amsterdam, The Netherlands) is Chairman of the Department of Medicine at the Academic Medical Center, University of Amsterdam. Oliver W. Press, MD, PhD (Seattle, WA) is Member and Penny E. Petersen Endowed Chair of Lymphoma Research, Fred Hutchinson Cancer Research Center, Professor of Medicine at the University of Washington. Linda J. Burns, MD (Minneapolis, MN) is Vice President and Medical Director, Health Services Research at National Marrow Donor Program/Be The Match. Michael A. Caligiuri, MD (Columbus, OH) is Director, Comprehensive Cancer Center, CEO, James Cancer Hospital & Solove Research Institute, JL Marakas Nationwide Insurance Enterprise Foundation Chair of Cancer Research, The Ohio State University.

Contents

1 Initial approach to the patient: History and physical examination 2 Examination of blood cells 3 Examination of the marrow 4 Consultative Hematology 5 Structure of the marrow and hematopoietic microenvironment 6 The organization and structure of lymphoid tissues 7 Hematology of the fetus and newborn 8 Hematology during pregnancy 9 Hematology in older persons 10 Genetic principles 11 Genomics 12 Epigenetics 13 Cytogenetic and Genetic Abnormalities 14 Metabolism of Hematological Neoplastic Cells 15 Apoptosis and Autophagy 16 Cell cycle regulation and hematological disorders 17 Signal transduction pathways 18 Hematopoietic stem cells, progenitors, and cytokines 19 The inflammatory response 20 Innate immunity 21 Adaptive immunity 22 Pharmacology and toxicity of antineoplastic drugs 23 Hematopoietic stem cell transplantation 24 Treatment of infections in the immunocompromised host 25 Antithrombotic therapy 26 Immune cell therapy 27 Vaccine therapy 28 Therapeutic apheresis: indications, efficacy, and complications 29 Gene transfer for therapy 30 Regenerative Medicine: Multipotential cell therapy for tissue replacement 31 Structure and Composition of the Erythrocyte Absorb former 30 Composition of Erythrocyte. 32 Erythropoiesis 33 Erythrocytes turnover 34 Clinical manifestations and classification of erythrocyte disorders 35 Aplastic anemia 36 Pure red cell aplasia 37 Anemia of chronic disease 38 Erythropoietic effects of endocrine disorders 39 The congenital dyserythropoietic anemias 40 Paroxysmal nocturnal hemoglobinuria 41 Folate, cobalamin and megaloblastic anemias 42 Iron Metabolism 43 Iron deficiency and overload 44 Anemia resulting from other nutritional deficiencies

Product Details

  • ISBN13: 9780071833004
  • Format: Hardback
  • Number Of Pages: 2528
  • ID: 9780071833004
  • weight: 4445
  • ISBN10: 0071833005
  • edition: 9th edition

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